Netherlands, MAASTRICHT
PhD Position in Neuro-Musculoskeletal Cell-Materials Atlas
Welcome to Maastricht University
Are you excited about pioneering the future of regenerative medicine? Do you want to work at the crossroads of Regenerative Medicine, biomaterials, organoid biology and developmental biology? Join the MERLN Institute and help us shape tomorrow's biomedical innovations as our new PhD candidate.
PhD Position in Neuro-Musculoskeletal Cell-Materials Atlas
- Our goal: Integrating spatiotemporal imaging, lineage-resolved cell tracing, and spatially resolved single-cell transcriptomic and proteomic profiling to map how extracellular material environments shape neuro-musculoskeletal tissue development and regeneration. - Your colleagues: An interdisciplinary team of biologists, chemists, and engineers within the MERLN Institute.
We are seeking a highly motivated PhD candidate to develop a cell-materials atlas of neuro-musculoskeletal development and regeneration. The project will investigate how musculoskeletal, neurovascular, and immune cell populations interact with dynamic extracellular environments during tissue formation and repair. To address this, the PhD candidate will combine human stem cell-based 3D in vitro models with datasets from organismal studies, building on recent advances in developmental atlases, spatial omics, and multimodal computational analysis.
A central focus of the project will be the integration of spatiotemporal imaging, lineage and cell tracing, and single-cell spatial multi-omics, including transcriptomic and proteomic approaches, to resolve how cell states emerge, interact, and reorganize across time and space. AI- and machine-learning-based tools will be used to analyze imaging data, integrate multimodal datasets, map spatial niches, and compare in vitro observations with organismal reference programs.
The project will also develop predictive models of spatiotemporally resolved cell-materials interactions, link...
Публикувано преди 6 ден(а)