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Declaration of interest regarding PhD project:
The Molecular Endocrinology Department (KMEB), Department of Clinical Research, University of Southern Denmark (SDU), invites applications for a 3-year PhD scholarship for a highly motivated candidate interested in working at the intersection of cancer biology and endocrinology. The project aims to investigate stanniocalcin-2 (STC2) as a key mediator of adipose tissue–tumor crosstalk in obesity-related cancer.
The project is part of a larger collaborative research initiative, the Molecular Mechanisms Linking Obesity and Cancer (MMLOC) network, funded by the Novo Nordisk Foundation. Though this grant, 2/3 of the PhD salary has been secured.
Employment is therefore conditional upon the successful enrolment of the candidate as a PhD student at the PhD School at Faculty of Health Sciences, and the awarding of a one-year Faculty Scholarship.
Research environment
The PhD project will be anchored at KMEB, a research unit focused on clinical and translational endocrinology, under the supervision of Associate Professor Rikke Hjortebjerg and Professor Jan Frystyk. The project will be conducted in close collaboration with the laboratory of co-supervisor Professor Henrik Ditzel, Cancer and Inflammation Research Unit, Department of Molecular Medicine, SDU.
The candidate will work across two complementary research groups with access to state-of-the-art research facilities. Together, the groups provide a multidisciplinary research environment with close integration of clinical and experimental research. The teams are internationally oriented and offer a supportive and inclusive research culture.
You can read more about KMEB here: https://www.sdu.dk/en/forskning/kmeb
Project description
Our research centers around the insulin-like growth factor (IGF) system, a key hormonal regulator in several diseases. The project focuses on stanniocalcin-2 (STC2), an IGF system member that is linked to poor outcomes in most obesity-related cancers but paradoxically predicts favorable prognosis in postmenopausal estrogen receptor-positive (ER+) breast cancer.
The aim is to examine how STC2 effects are modulated by obesity and estrogen signaling and how it regulates IGF-2/insulin receptor pathways in the tumor–adipose microenvironment. To establish clinically relevant models, the candidate will generate patient-derived xenograft (PDX) mouse models with human tumor tissue and participate in establishing patient-derived organoids and 3D co-cultures. These systems will be interrogated using genetically engineered STC2 and PAPP-A variants and analyzed with advanced sequencing, spatial, and single-cell omics.
The PhD student will:
Establish and analyze PDX mouse models of ER+ breast cancer.
Sample and process tumor and tumor-adjacent/distant adipose tissue from breast cancer patients.
Assess STC2 activity, IGF-2 signaling, and tumor growth under estrogen-controlled conditions.
Help analyze molecular data generated through sequencing and omics-based approaches.
Qualifications
The applicant should possess the following qualifications:
A master’s degree (MSc or equivalent) in molecular biology, biomedicine, or related fields.
Preferably prior experience with endocrinology or cancer research.
An interest in working with animal models (mice) is a necessity.
Excellent communication skills in English, both written and spoken.
A motivated, independent, and quality-oriented approach to research, with enthusiasm for learning new scientific disciplines and methodologies.
For further information about the project, please contact:
Rikke Hjortebjerg
KMEB, Department of Clinical Research
University of Southern Denmark (SDU)
E-mail: rhjortebjerg@health.sdu.dk
Applications must include:
• At letter stating the interest, motivation and qualifications for the project (max. 2 pages) - upload under “Application form”.
• Detailed CV, including personal contact information
• Certified copy of diploma (Master’s degree in a relevant field)
Further information about the PhD-study can be found at the homepage of the University.
Applications must be submitted electronically using the link "Apply now". Attached files must be in Adobe PDF format. We strongly recommend that you read How to apply for a position at SDU before you apply.
Incomplete applications and applications received after the deadline will neither be considered nor evaluated. This also applies to reference letters.
Closing date September 1, 2026
Successful candidates will be asked to send an application to the PhD Secretariat, Faculty of Health Sciences, to be enrolled as PhD students.
The PhD programme will be carried out in accordance with Faculty regulations and the Danish Ministerial Order on the PhD Programme at the Universities (PhD order)
Salary and Working Conditions at SDU
PhD students employed at SDU are employed as PhD fellows according to the Danish Confederation of Professional Associations in public employment (AC) agreement.
Salary and any salary supplement are paid according to your seniority level and as negotiated with your union representative. The base salary (excluding 18.07% pension contribution) is DKK 374,912.98.
The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.
European Passport or Valid EU Work Permit Required
Please read before applying.
Due to Danish immigration regulations, we are only able to consider applicants who hold a valid European passport or already have the legal right to work in Denmark or another EU country.
Applications from candidates without a European passport or valid EU work permit will not receive a reply.
Join the Team at Ærø Hotel – Denmark's Only Adults-Only Hotel
Are you looking for an exciting opportunity to live and work in Denmark?
Ærø Hotel is currently looking for 2 motivated employees to join our international team. We especially welcome couples, as many of our positions can be combined across departments, allowing you to work and live together.
We Are Hiring For
Housekeeping
Restaurant / Waiter Service (Breakfast & Dinner)
Kitchen (Breakfast & Evening)
Many of our employees work across several departments, creating varied workdays, flexible schedules and stable full-time employment.
About Ærø Hotel
Ærø Hotel is a family-owned and family-operated hotel located in the charming maritime town of Marstal on the beautiful island of Ærø, Denmark.
We offer:
100 hotel rooms
Around 35,000 overnight stays every year
Restaurant and Compass Bar
Conference and event facilities
Indoor swimming pool
Fitness room
An international working environment
We are proud to be Denmark's only adults-only hotel, welcoming guests aged 18 years and above.
Our team consists of employees from several European countries. English is the primary working language, and Spanish is also spoken in our kitchen, making Spanish-speaking applicants especially welcome.
Your Responsibilities
Housekeeping
Cleaning guest rooms and public areas
Changing bed linen and towels
Restocking guest amenities
Ensuring rooms meet hotel quality standards
Restaurant / Waiter Service
Serving breakfast and dinner
Guest service and table service
Preparing the restaurant before and after service
Maintaining high service standards
Kitchen (Breakfast & Evening)
Assisting with breakfast and dinner preparation
Basic food preparation
Plating meals
Dishwashing and kitchen cleaning
Maintaining a clean and organised kitchen
Following food safety and hygiene procedures
We Are Looking For People Who
Speak English or Spanish
Are reliable, positive and responsible
Enjoy working in hospitality and as part of a team
Thrive in a busy working environment
Are flexible regarding working hours and departments
Have previous experience in hotels, restaurants, housekeeping or kitchens (preferred but not essential)
Are motivated to learn and contribute to a positive workplace
What We Offer
Full-time employment
Immediate start
Stable year-round workplace
Friendly and international colleagues
Thorough introduction and training
Opportunities to work across multiple departments
Staff accommodation available
Beautiful island surroundings and an excellent work-life balance
Staff Accommodation
Accommodation is available approximately 10 minutes' walk from the hotel.
Each employee has a private bedroom with shared kitchen and bathroom facilities.
Rent: EUR 100 per person per week, including:
Electricity
Water
Heating
Internet
Salary
Starting salary before tax + 12.5% Danish holiday pay
Housekeeping
DKK 125/hour (approximately EUR 16.75)
Restaurant / Waiter Service
DKK 135/hour (approximately EUR 18.10)
Kitchen (Breakfast & Evening)
DKK 140/hour (approximately EUR 18.75)
Employment Details
Start date: As soon as possible.
Location:
Ærø Hotel
Marstal, Denmark
How to Apply
Please send your application by email to:
Nick Hulegaard
General Manager
Please attach:
CV
Short application or cover letter
Recent photo
Relevant references (if available)
Applications are reviewed continuously, and interviews are conducted on an ongoing basis. Positions will be filled as soon as suitable candidates are found.
We look forward to welcoming new colleagues to Ærø Hotel and hope to hear from you soon!