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If you want to start your scientific career in biophotonics while working towards real-world impact in healthcare, this opportunity is for you.
DTU Health Tech invites applications for a PhD researcher investigating how tissue optics can improve both the imaging depth of optical coherence tomography and the sensitivity of this method for detecting pancreatic cancer. Funded by the ERC Synergy Grant Zee-Zoom-Zap, the position will be part of the Biophotonic Imaging Group in the Optical Imaging and Sensing (OASIS) section. You will be joining a dynamic, collaborative and interdisciplinary team where you will get all the necessary support to turn your ideas into great results. Additionally, you will be part of a vibrant international collaboration with opportunities to expand your knowledge through external research visits.
In the Biophotonic Imaging Group, our aim is to drive cutting-edge research in multimodal, functional optical bio-imaging, and to establish a biophotonic imaging resource for translational research at DTU Health Tech. We develop and innovate new optical imaging concepts and technologies that enable novel insights into tissue function and disease biomarkers, and new clinical achievements that improve healthcare.
Pancreatic cancer is the 12th most common cancer, but one of the deadliest, with a 5-year survival rate around 13%. This poor prognosis is due to the lack of screening technologies that can detect pancreatic cancer at an early stage – diagnosis at stage Ia would increase the 5-year survival rate 10-fold. This is your opportunity to contribute to the development of an exciting new theragnostic platform for screening, early diagnosis, and in situ treatment of pancreatic cancer.
We are looking for a candidate with experience in experimental optics to explore how novel fluorophores can enhance the imaging depth achievable with cancer-specific fluorescence imaging. Fluorophores that emit light in the second biological window (NIR-II, 1000-1700 nm), experience less optical scattering and therefore can be detected deeper in tissue. Your role will be to investigate the imaging depth that can be achieved with the candidate probes and to explore the optimal collection protocols to ensure optimal imaging depth. This work will be undertaken in close collaboration with the team developing the novel fluorophores. Additionally, you will investigate how the combination of fluorescence imaging, confocal reflectance imaging, and optical coherence tomography can aid in the detection of pancreatic cancer. Your work will be applied through experimental investigations on human and animal pancreas tissue.
Responsibilities and qualifications
Your overall focus will be to investigate the limits of imaging depth with NIR-II fluorophores. You will contribute to the development and characterization of novel fluorophores and design an imaging system for optimal signal collection. You will contribute to the development of imaging processing protocols for localizing the fluorescence signal in depth. Your work will be experimentally validated in tissue phantoms and ex vivo pancreas tissue with the aim of developing novel cancer biomarkers and protocols for tumour margin detection.
Your primary tasks will be to:
- Investigate links between tissue optical properties, fluorophore properties, and the maximum imaging depth that can be achieved with NIR-II fluorophores
- Develop protocols to characterize the performance and properties of novel NIR-II fluorophores
- Develop an optimized fluorescence detection system for collecting signals withing the pancreatic duct
- Develop image processing protocols for localization of the fluorescence signal deep in tissue, taking advantage of AI modelling
- Collaborate with a tightly linked international team
- Co-supervise BSc and MSc students
- Disseminate your work through journal publications and participation in scientific conferences
You must have a two-year master's degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master's degree. Your background should preferably be in applied physics, biophotonics, biochemistry or photonics engineering, i.e., a solid background in optics, photonics and optical imaging. Knowledge of fluorescence microscopy/spectroscopy, biochemistry and data processing is an asset. We expect the candidate to have strong laboratory skills in the above areas. Good communication skills in written and spoken English is a must.
Approval and Enrolment
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see DTU's rules for the PhD education
.
We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.
Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.
The period of employment is 3 years. Starting date is 1 September (or according to mutual agreement). The position is a full-time position.
You can read more about career paths at DTU here
.
Further information
Further information may be obtained from Peter E. Andersen (peta@dtu.dk).
You can read more about DTU Health Tech at www.healthtech.dtu.dk/
.
If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark
. Furthermore, you have the option of joining our monthly free seminar “PhD relocation to Denmark and startup “Zoom” seminar
” for all questions regarding the practical matters of moving to Denmark and working as a PhD at DTU.
Application procedure
Your complete online application must be submitted no later than 15 June (23:59 Danish time)
. Applications must be submitted as one PDF file
containing all materials to be given consideration. To apply, please open the link "Apply now", fill out the online application form, and attach all your materials in English in one PDF file
. The file must include:
- A letter motivating the application (cover letter)
- Curriculum vitae
- Grade transcripts and BSc/MSc diploma (in English) including official description of grading scale
You may apply prior to obtaining your master's degree but cannot begin before having received it.
Applications received after the deadline will not be considered.
All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. As DTU works with research in critical technology, which is subject to special rules for security and export control, open-source background checks may be conducted on qualified candidates for the position.
DTU Health Tech
With a vision to improve health and quality of life through technology, DTU Health Tech engages in research, education, and innovation based on technical and natural science. We educate tomorrow’s health tech engineers and create the foundation for new and innovative services and technologies for the globally expanding healthcare sector with its demands for the most advanced technological solutions. DTU Health Tech’s expertise can be described through five overall research areas: Diagnostic Imaging, Digital Health, Personalised Therapy, Precision Diagnostics, and Sensory and Neural Technology. Our technologies and solutions are developed with the aim of benefiting people and creating value for society. The department has a scientific staff of about 210 persons, 140 PhD Students, and a technical/administrative support staff of about 100 persons of which a large majority contributes to our research infrastructure and related commercial activities.
DTU – For the benefit of society since 1829
DTU is one of Europe's leading elite technical universities. Through research and education at an international top level, we create solutions to the major societal challenges of our time and help secure Europe's global leadership in sustainable technological development. Since Hans Christian Ørsted founded DTU almost 200 years ago, our mission has remained the same: We develop and create value through the natural and technical sciences for the benefit of society. DTU has 13,800 students, 1,600 PhD students, and 6,500 employees. We work in an international environment and have an inclusive, stimulating, and informal work culture. DTU has campuses in all parts of Denmark and in Greenland and collaborates with the best universities around the world.
If you want to start your scientific career in biophotonics while working towards real-world impact in healthcare, this opportunity is for you.
DTU Health Tech invites applications for a PhD researcher investigating how tissue optics can improve both the imaging depth of optical coherence tomography and the sensitivity of this method for detecting pancreatic cancer. Funded by the ERC Synergy Grant Zee-Zoom-Zap, the position will be part of the Biophotonic Imaging Group in the Optical Imaging and Sensing (OASIS) section. You will be joining a dynamic, collaborative and interdisciplinary team where you will get all the necessary support to turn your ideas into great results. Additionally, you will be part of a vibrant international collaboration with opportunities to expand your knowledge through external research visits.
In the Biophotonic Imaging Group, our aim is to drive cutting-edge research in multimodal, functional optical bio-imaging, and to establish a biophotonic imaging resource for translational research at DTU Health Tech. We develop and innovate new optical imaging concepts and technologies that enable novel insights into tissue function and disease biomarkers, and new clinical achievements that improve healthcare.
Pancreatic cancer is the 12th most common cancer, but one of the deadliest, with a 5-year survival rate around 13%. This poor prognosis is due to the lack of screening technologies that can detect pancreatic cancer at an early stage – diagnosis at stage Ia would increase the 5-year survival rate 10-fold. This is your opportunity to contribute to the development of an exciting new theragnostic platform for screening, early diagnosis, and in situ treatment of pancreatic cancer.
We are looking for a candidate with experience in tissue optics and who is comfortable working in a photonics lab to explore how spatial offset optical coherence tomography (SO-OCT) can be advanced for cancer detection over a large depth range in tissue. SO-OCT is a new technology pioneered at DTU that leverages multiply scattered light to extend the imaging depth of OCT, potentially beyond, potentially beyond 5 mm and thereby revolutionize non-invasive diagnostics. Your role will be to explore the link between tissue optical properties, offset magnitude range, spatial resolution, and the maximum achievable imaging depth with SO-OCT. Additionally, you will investigate how optical properties including the scattering coefficient and polarization properties of tissue can be used to improve the sensitivity of SO-OCT for cancer detection. Your work will be applied through experimental investigations on human and animal pancreas tissue.
Responsibilities and qualifications
Your overall focus will be to investigate the limits of imaging depth with SO-OCT, with an emphasis on exploring the role of tissue optical properties. You will additionally contribute to the development of a modelling framework for extracting optical properties from SO-OCT images. Your modelling work will be experimentally validated in tissue phantoms and ex vivo pancreas tissue with the aim of developing novel cancer biomarkers and protocols for tumour margin detection.
Your primary tasks will be to:
- Investigate links between tissue optical properties, offset magnitude, spatial resolution, and the maximum achievable imaging depth with SO-OCT.
- Develop frameworks for extracting optical properties from SO-OCT images including scattering coefficient, anisotropy, birefringence, depolarization, etc.
- Investigate experimentally how SO-OCT and optical properties can aid in cancer detection deep in tissue, taking advantage of AI modelling
- Collaborate with a tightly linked international team
- Co-supervise BSc and MSc students
- Disseminate your work through journal publications and participation in scientific conferences
You must have a two-year master's degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master's degree. Your background should preferably be in applied physics, biophotonics, or photonics engineering, i.e., a solid background in optics, photonics, optical imaging and data processing is an asset, and knowledge of microscopy is an advantage. We expect the candidate to have strong laboratory skills in the above areas. Good communication skills in written and spoken English is a must.
Approval and Enrolment
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see DTU's rules for the PhD education
.
We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.
Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.
The period of employment is 3 years. Starting date is 1 September (or according to mutual agreement). The position is a full-time position.
You can read more about career paths at DTU here
.
Further information
Further information may be obtained from Peter E. Andersen (peta@dtu.dk).
You can read more about DTU Health Tech at www. www.healthtech.dtu.dk/
.
If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark
. Furthermore, you have the option of joining our monthly free seminar “PhD relocation to Denmark and startup “Zoom” seminar
” for all questions regarding the practical matters of moving to Denmark and working as a PhD at DTU.
Application procedure
Your complete online application must be submitted no later than 15 June 2026 (23:59 Danish time)
. Applications must be submitted as one PDF file
containing all materials to be given consideration. To apply, please open the link "Apply now", fill out the online application form, and attach all your materials in English in one PDF file
. The file must include:
- A letter motivating the application (cover letter)
- Curriculum vitae
- Grade transcripts and BSc/MSc diploma (in English) including official description of grading scale
You may apply prior to obtaining your master's degree but cannot begin before having received it.
Applications received after the deadline will not be considered.
All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. As DTU works with research in critical technology, which is subject to special rules for security and export control, open-source background checks may be conducted on qualified candidates for the position.
DTU HealthTech
With a vision to improve health and quality of life through technology, DTU Health Tech engages in research, education, and innovation based on technical and natural science. We educate tomorrow’s health tech engineers and create the foundation for new and innovative services and technologies for the globally expanding healthcare sector with its demands for the most advanced technological solutions. DTU Health Tech’s expertise can be described through five overall research areas: Diagnostic Imaging, Digital Health, Personalised Therapy, Precision Diagnostics, and Sensory and Neural Technology. Our technologies and solutions are developed with the aim of benefiting people and creating value for society. The department has a scientific staff of about 210 persons, 140 PhD Students, and a technical/administrative support staff of about 100 persons of which a large majority contributes to our research infrastructure and related commercial activities.
DTU – For the benefit of society since 1829
DTU is one of Europe's leading elite technical universities. Through research and education at an international top level, we create solutions to the major societal challenges of our time and help secure Europe's global leadership in sustainable technological development. Since Hans Christian Ørsted founded DTU almost 200 years ago, our mission has remained the same: We develop and create value through the natural and technical sciences for the benefit of society. DTU has 13,800 students, 1,600 PhD students, and 6,500 employees. We work in an international environment and have an inclusive, stimulating, and informal work culture. DTU has campuses in all parts of Denmark and in Greenland and collaborates with the best universities around the world.
Department of Clinical Medicine
As a Post-Doc at the Department of Clinical Medicine, you will be part of what is probably the largest health science research department in Denmark. Our clinical research covers all the medical specialities and takes place in close collaboration with the university hospital and the regional hospitals in the Central Denmark Region. We have approx. 30,000 square metres of modern research facilities for experimental surgery and medicine, animal facilities and also advanced scanners at our disposal. The department has overall responsibility for the Master's degree programs in medicine and in molecular medicine. At the department we are approx. 670 academic employees, 500 PhD students and 160 technical/administrative employees who are cooperating across disciplines. As a postdoc, you will be working at Aarhus University in the Central Denmark Region. You can read more about the department here and about the faculty here.
About the research project
We are seeking a highly motivated postdoctoral researcher to join the QuantuMRI programme, funded by the Novo Nordisk Foundation’s Interdisciplinary Synergy Programme and carried out in collaboration between Aarhus University, the Weizmann Institute of Science, and collaborators in Argentina. QuantuMRI aims to bridge quantum sensing and MRI to achieve imaging beyond the limits of conventional voxel-based imaging. The project will involve theoretical and computational work, with particular emphasis on physics-based simulations, biophysical modelling of signal formation and transfer mechanisms, and assessment of experimental feasibility in quantum-enhanced MRI. Depending on the candidate’s profile and the development of the project, the position may also include experimental activities in Aarhus and/or at Weizmann. We therefore welcome applicants who combine strong analytical skills with initiative, independence, and the ability to shape and drive their own research direction within a collaborative framework. The ideal candidate will contribute original ideas and complementary expertise in areas such as MRI/NMR physics, quantum sensing, biophysical modelling, or numerical methods.
Your job responsibilities
As a Postdoc in Quantum Enhanced MRI your position is primarily research-based but may also involve teaching assignments. You will contribute to the development of the department through research of high international quality. In your daily work, you will interact closely with colleagues and collaborators across the consortium, while being expected to develop and pursue independent ideas within the project framework
Your main tasks will consist of:
- Independent research of high international quality, including publication.
- Development of physics-based and biophysical models relevant to quantum-enhanced MRI.
- Numerical simulations and analytical work aimed at understanding signal formation, magnetization transfer, and experimental feasibility in low-field MRI and quantum-sensing-based readouts.
- Contribution to the design, implementation, and analysis of NMR/MRI experiments, including saturation-transfer and related contrast mechanisms.
- Collaboration with project partners at Aarhus University, the Weizmann Institute of Science, and the collaborating lab at CNEA/CONICET in Argentina, including participation in consortium activities and annual workshops.
- Dissemination of research through conference presentations and scientific meetings.
You will report to Professor Sune Nørhøj Jespersen.
Your competences
You have academic qualifications at PhD level, preferably within physics, chemistry, biomedical engineering, or a related field. Candidates with experience in MRI/NMR, numerical simulations, and quantitative modelling are preferred. Experience with quantum sensing, magnetization transfer, low-field magnetic resonance, or related experimental and theoretical methods will be considered an advantage. We are looking for a candidate with strong analytical skills, scientific curiosity, and the ability to work both independently and collaboratively in an interdisciplinary and international research environment.
As a person, you have good interpersonal skills, are inclusive and team-oriented and able to contribute to a good work environment. We expect you to be fluent in oral and written English.
In order to be assessed as qualified for a Postdoc position, you must meet these academic criteria.
Shortlisting will be used.
To be considered for the position, applicants must meet the formal requirements for academic appointments at Aarhus University and submit all required application materials by the deadline. Applications that are substantially incomplete will not proceed to further assessment
Questions about the position
If you have any questions about the position, please contact Professor Sune Nørhøj Jespersen, sune@cfin.au.dk.
Your place of work will be at the Center of Functionally Integrative Neuroscience, Department of Clinical Medicine, Universitetsbyen 3, DK-8000 Aarhus C, Denmark.
We expect to conduct interviews in week 25.
Terms of employment
- Appointment as a postdoc requires academic qualifications at PhD level.
- Further information on the appointment procedure can be found in the Ministerial Order on the Appointment of Academic Staff at Universities.
- The appointment is in accordance with the Danish Confederation of Professional Associations (Akademikerne).
- Remuneration is in accordance with the above, and the Salary agreement catalogue for staff at Health.
- The yearly base salary for a fulltime postdoc is between DKK 484.214,84 and DKK 538.720,20 depending on the years of working experience after achieved MSc degree. The base salary includes a position related supplement and pension (17.1 %). Additional supplement(s) for special qualifications can be negotiated. Authorisation supplemement(s) will be granted, if relevant for the position. Your local eligible trade union representative at Aarhus University negotiates your salary on your behalf.
- Researchers recruited from abroad are offered a special researcher tax scheme with a lower tax rate.
- Further information on qualification requirements and job description can be found in the Ministerial Order on Job Structure for Academic Staff
Application
Your application must include the following:
- Motivated application
- Curriculum Vitae
- Diploma
- Template for applicant - postdoc
- A list of publications
- A teaching portfolio. We refer to Guideline on the use of teaching portfolios
- A maximum of five of the publications of greatest relevance to the job may be submitted (optional)
- Research plan can be uploaded (optional)
- Coauthor statement(s) can be uploaded (optional)
- References/recommendations can be uploaded separately in the e-recruitment system (optional)
Aarhus University’s ambition is to be an attractive and inspiring workplace for all and to foster a culture in which each individual has opportunities to thrive, achieve and develop. We view equality and diversity as assets, and we welcome all applicants.
International applicant?
Aarhus University offers a broad variety of services for international researchers and accompanying families, including assistance with relocation and career counselling to expat partners. Please find more information about the International Staff Office and the range of services here. Aarhus University also has a Junior Researcher Association and offers career development support. You can read more about these resources here.
The application must be submitted via Aarhus University’s recruitment system, which can be accessed under the job advertisement on Aarhus University's website.
Aarhus University
Aarhus University is an academically diverse and research-intensive university with a strong commitment to high-quality research and education and the development of society nationally and globally. The university offers an inspiring research and teaching environment to its 37,000 students (FTEs) and 8.700 employees and has an annual revenue of EUR 1.106 billion. Learn more at www.international.au.dk/